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tonic and blood purifier [10]. C. asiatica contains various flavonoids. In order to investigate if antibodies were exerting an effect on invasion, serial dilutions of mAb anti-CSP were tested in the culture medium. After synchronisation, the percentage of schyzonts varied from 88 to 90% [Initial % parasitaemia was 1.98 +/- 0.11 (mean +/- SD)]. Parasites were cultured for 24h and ring-stage infected erythrocytes were counted [control ring-stage % parasitaemia was 3.07 +/- 0.73 (mean +/- SD)]. Efficacy of invasion was calculated as the percentage of ring infected erythrocytes of test cultures over the percentage of ring infected erythrocytes in control culture (Fig. 2). When anti-CSP mAb was present in the culture we observed a dose dependent decrease in invasion, that was inverted when parasites were treated with the lowest concentration (1ng/ml mAb) presenting an increase of invasion. Although, close to significant level this increase was not significantly different from the control (p=0.0578).. The pathophysiology of the spinal abnormalities in Stickler syndrome has not been fully defined. Fibrillar collagen mutations associated with the syndrome (COL2A1, COL11A1, and COL11A2) presumably lead to malformation and weakening of intervertebral disks and vertebral end plates. Rose et al assumed that the vertebral abnormality is probably a result of abnormal vertebral growth with exacerbation by premature degenerative changes in adulthood [8]..
IL-7 and estrogen deficiency-induced bone loss. This report is the first to show the importance of several elements of both NF-κB pathway in maintaining the ovarian cancer stem cell population..
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