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It is noteworthy that the incretin-like effect of gastrin (reflected by an almost 2-fold higher integrated insulin response) was demonstrated upon synthetic human gastrin-17 infusion at the lowest dose which increased circulating gastrin by the same order of magnitude as those observed for maximal concentrations of endogenous gastrin (about 3-fold) after a protein-rich meal .. advantage of this approach is that large amount of published data. The SUN cohort followed-up prospectively 5880 Spanish men and women older than 20 years of age, all university graduates. Dietary information was gathered at baseline with a previously validated semiquantitative food frequency questionnaire. New cases of medically diagnosed hypertension (HT) were identified through responses to a mailed questionnaire after at least 2 years from recruitment. The SUN cohort followed-up prospectively 5880 Spanish men and women older than 20 years of age, all university graduates. 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